DESCRIPTION OF THE COMPANY

Tissium is a mission-driven medical device company founded in 2013, headquartered in Paris, with a production facility in Roncq (near Lille) and an office in Boston. We are dedicated to creating a new era of body repair by leveraging our biopolymer platform to develop innovative solutions in surgery for a positive impact on patients' lives.

Tissium’s technology is based on research and intellectual property from the laboratories of Professor Robert Langer (MIT) and Professor Jeffrey M. Karp (Brigham and Women's Hospital), who co-founded the company with Christophe Bancel (CEO) and Maria Pereira (Deputy CEO & Chief Innovation Officer).

We are developing polymers for atraumatic tissue repair in various applications. Today, these polymers are used for sutureless nerve repair, hernia repair, and cardiovascular sealing.

Since our inception, we have raised a total of 170 million euros. Our latest fundraising round, which concluded in April 2023, resulted in 50 million euros in additional funding. This infusion of capital provides us with the necessary resources to finance the commercialization of our first products.

About the Role

The Clinical Research Scientist is a key member of the Global Clinical Affairs team, providing scientific and medical expertise across the lifecycle of clinical development activities. This role supports the design, execution, and oversight of clinical evaluations, risk management activities, and clinical studies to ensure scientific rigor, regulatory compliance, and high-quality data generation.

The Clinical Research Scientist collaborates closely with cross-functional teams including Clinical Operations, Data Science, Quality, Regulatory Affairs, and R&D to support clinical strategy, study execution, and the preparation of clinical documentation (e.g., clinical evaluation plans and reports, study protocols, regulatory submissions, and project deliverables).

Key Responsibilities

• Author and maintain clinical documentation including Clinical Evaluation Plans (CEP), Clinical Evaluation Reports (CER), study protocols, protocol amendments, informed consent forms, clinical study reports, risk management documentation, and scientific publications.

• Conduct comprehensive scientific literature reviews and evaluate clinical, scientific, and risk data in alignment with current clinical practice and regulatory expectations (EU MDR / FDA).

• Define and execute end-to-end data analysis strategies to address key scientific and clinical questions, including:

1. Defining study populations

2. Developing analytical models

3. Interpreting outcomes

4. Generating meaningful insights

• Present and communicate clinical and scientific findings clearly and effectively to internal stakeholders, senior leadership, regulatory authorities, and at industry or investigational meetings.

• Contribute to the development of clinical strategy and trial design through cross-functional collaboration with Clinical Affairs, R&D, Regulatory Affairs, Marketing, Risk Management, and Clinical Operations.

• Manage or support clinical study timelines and budgets, including vendor selection, CRO oversight, medical writer coordination, and monitoring of expenditures in alignment with approved budgets.

• Support regulatory submissions and health authority interactions in collaboration with Regulatory Affairs.

• Participate in audits and contribute to the continuous improvement of clinical processes, SOPs, and work instructions.

• Interface with senior management on complex matters requiring coordination across internal departments, physicians, external CROs, and partners.

• Support the development of team members through training, mentorship, and knowledge sharing.

• Contribute to quality initiatives, including root cause analysis, corrective and preventive actions (CAPA), and effectiveness monitoring.

• Exercise sound scientific and clinical judgment independently while managing projects of substantial scope, complexity, and cross-functional impact.

REPORTING LINE

This job will report to the Associate Director, Clinical Science.

YOU WILL LOVE THIS JOB IF

• You are eager to learn, apply, and share knowledge, and you actively promote a culture of continuous improvement.

• You are highly organized and detail-oriented.

• You are autonomous, proactive, and responsive, with a strong solutions-focused mindset.

• You work effectively independently and collaboratively as part of a team.

• You maintain a positive attitude, follow instructions well, and thrive in a structured environment.

• You are strongly motivated to contribute to improving patients’ quality of life.
  

YOUR BACKGROUND 

• Master’s degree or Advanced degree (PhD, MD, or equivalent) in a scientific, medical, engineering, or related field.

• Minimum of 2 years of relevant experience in the medical device industry, or an equivalent combination of education and professional experience.

• Strong independent data analysis and programming skills (e.g., R, SAS, SPSS, MATLAB or similar statistical tools).

• Proven experience in data visualization and scientific figure preparation for reports, publications, or regulatory submissions.

• Solid understanding of statistical methodologies and their application in clinical research.

• Fluency in English (written and spoken).

WHY JOIN US 

• Thrive in a stimulating environment with a work culture that values urgency, a willingness to take risks, a passion for learning, the ability to challenge the status quo, and the agility to operate in a dynamic setting.

• Grow your career: At TISSIUM, we invest in our people through tailored training and professional development programs. We believe in offering diverse learning methods to help each team member flourish in their career journey.

• Be part of an ambitious start-up tackling one of the most persistent medical challenges since the advent of surgical procedures.

• Work with purpose: Environmental, Social, and Governance (ESG) principles have been embedded in our business model from the very beginning. As we grow, strengthening and advancing our ESG strategy and commitments remains a top priority.

• Enjoy competitive benefits: Work-life balance | Flexible remote work options | Attractive total compensation | Internal and geographic mobility opportunities across our locations (Paris HQ, Boston office, and Roncq industrial site).

• Join a truly international team: Collaborate with colleagues from over 19 nationalities, reflecting TISSIUM’s commitment to diversity and the strength it brings to our work.

HIRING PROCESS

• The process starts with a 30-minute interview with our Talent Acquisition Manager.

• You will then meet the hiring manager for a one-hour interview.

• Shortlisted candidates will be invited to a Technical Interview.

• For the final stage, you will meet key stakeholders and other members of the Tissium team for a team and culture fit interview.

In some cases, we may also request professional references (including contact details).

Intrigued? We’d love to hear from you! Apply today - we’re standing by for your resume!

👉 We believe that building an inclusive company starts with a diverse team. We value diversity and encourage applications from people of all backgrounds. We are committed to equal opportunity and do not tolerate discrimination of any kind, including on the basis of gender, gender identity or expression, sexual orientation, origin, family situation, age, beliefs, disability, health status, or any other characteristic protected by law.

Our recruitment process is designed to be simple, transparent, and conversation-driven. We prioritize human interaction and ensure that every application is reviewed carefully and fairly.